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Dr. Enrique Jacome |
Endocrine hormones are vital to health and well-being. It is critical that these chemicals exist in balance in order to perform as they are intended to. Without question, living with abnormally low levels of hormones, as occurs in menopause or andropause, upsets that balance and sends an open invitation to the physical, emotional and mental decline of aging and the chronic diseases that accompany it.
The case for hormone replacement is compelling. Unlike the early days when HRT was basically an experiment designed to reduce menopause symptoms and backed by pharmaceutical marketing campaigns rather than long term studies, recent research is redefining the present-day approach.
A large body of scientific evidence already exists substantiating the effects (both positive and negative) of today’s HRT modalities. This important data will continue to accrue as current investigative outcomes are evaluated and more studies are undertaken.
Many practitioners now recognize menopause and andropause for what they are—wellness issues, and employ modalities that go beyond simply relieving symptoms. This more enlightened approach will help millions of people—those who wish to live longer and stay healthier as they age—to make better health choices.
THE STRONG CASE FOR HORMONE REPLACEMENT
Endocrine hormones serve as the powerful chemical messengers that keep the body running in tiptop shape. They flow through the bloodstream around the clock, traveling to specific cells in order to orchestrate many of the body’s internal functions, including the behavior of vital organs. Even a small fluctuation in levels can cause big changes in cells or disturb the balance throughout the entire body. Too much or too little of a hormone can have someone suffering serious consequences.
This is why the hormone deficiencies associated with menopause and andropause are so disruptive to a person’s health. As hormone production subsides, a person is literally wasting away on the inside—becoming frailer, losing muscle and bone mass, developing clogged arteries and losing mental acuity. The quality of life plummets at the same time the risk for many degenerative diseases skyrockets.
Noted physicians Erika Schwartz and Kent Holtorf, published a seminal review of literature in 2008. In their article, they surveyed the outcomes of 267 studies which addressed the safety and efficacy aspects of various hormone replacement therapies. Their research literature was dated as far back as 1941 and centered on subjects ranging from the role played by conjugated and synthetic hormones in the increased risk of various types of cancer, to the positive impact of restored estradiol and testosterone levels on osteoporosis and cardiovascular disease when using bio-identicals. At end, Schwartz and Holtorf concluded unequivocally that hormone replacement has indeed been shown to be an important tool in wellness and prevention. Additionally, they found that the type of hormone therapies chosen for patients is what makes the difference and must be carefully considered.[1]
THE CONTROVERSY
It’s true that widespread disparity exists between hormone replacement physicians as to which hormones are the most important to replenish. If you’ve ever done an Internet search on the topic, you likely came up with no less than MILLIONS of websites suggesting a variety of solutions. These websites represent a wide range of opinions and endorsements; everything from organizations, medical groups and drug companies to HRT physicians, insurance companies and even celebrities. You’ll find some recommending estrone or progesterone replacement as the panacea; others say it’s your DHEA, pregnenalone or human growth hormone (HGH) that need restoring; while still others prescribe testosterone and any or all of the three estrogens. And then there are the proponents of soy and herbals and so on. When so many are offering such varied solutions, it’s hard to imagine how patients can make sense of it.
Bottom line—there really isn’t an across the board consensus in the medical community, and despite the building evidence on bio-identicals and the importance of using the proper delivery method, there probably won’t be for some time. However, there is a certain level of agreement since the most common replacement today generally consists of some form of estrogen combined with some form of progesterone. Testosterone is also at times included.
THE KEY IS HORMONAL BALANCE
Hormone replacement is complex, especially when the desired outcome is a return to homeostasis. You cannot randomly take any hormone or substance in any amount and expect to achieve hormonal balance. In order to regain this internal state, the method must be precise, available 24/7 and based on replacing the essential missing hormones with those that are biologically identical.